Christina Quinn is one of three English tourists who died after the "tragic incident" off the coast of Marsa Alam.
The 58-year-old was serving as the chief executive of St Luke's Hospice in Plymouth after years of working on the frontline.
Last night her family spoke highly of the "rock to many" who will be "missed beyond words".
Sources say Ms Quinn was with the two other victims inside their cabin rooms when the deadly fire broke out in the Red Sea on Sunday.
Paying tribute, a family spokesperson told Sky News: "It is with great sadness that we confirm the tragic death of Christina Quinn in Egypt.
"She was a sister, daughter, wife, aunty, friend, and rock to many.
"She will be missed beyond words. We would ask for privacy at this time."
Charles Hackett, chair of St Luke's Hospice, said: "Christina was incredibly passionate about St Luke's and its place at the heart of the community it serves.
"We are devastated to lose her warmth, wisdom and leadership.
"We will miss Christina enormously and our hearts go out to her family and close friends at this tragic time."
Scuba Travel, who chartered the boat, confirmed three British tourists had "perished in the tragic incident".
An investigation into the deaths revealed that the three had been found in the deck in their cabins.